2020

A new generation of optogenetic tools for research and medicine

The European Research Council (ERC) is providing 10 million euros in funding for an interdisciplinary, collaborative project to structurally and biophysically analyze selected photo-receptors and develop them into “OptoGPCRs”, light-controlled molecular switches with a wide range of applications in biology and medicine. 

Read more … A new generation of optogenetic tools for research and medicine

Surprising insights into the role of autophagy in neurons

It appears that autophagy protects our neurons in the brain, but evidently for entirely different reasons than previously assumed, as researchers from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) and Charité in Berlin have now shown. These fundamentally new findings have now been published in the prestigious journal “Neuron”.

Read more … Surprising insights into the role of autophagy in neurons

Falling Walls Winner

We are Falling Walls Finalists! Watch our science breakthrough in the Science and Innovation Management Category here: Enable the next impact-driven generation of scientists
Register for free to join the virtual showcase of the Science Breakthroughs of the Year from 1 – 10 November 2020

Read more … Falling Walls Winner

International Festival of Science in Berlin and Remote

Ten days of research, innovation and international exchange - Berlin Science Week and Falling Walls invite you to a Remote World Science Summit this year. With more than 200 virtual discussion events, workshops, exhibitions and performances, the organizers defy the pandemic and want to promote a deeper understanding of the world. Neuroscientists will discuss, for example, how to deal with dementia.

Read more … International Festival of Science in Berlin and Remote

Emmanuelle Charpentier honoured with the 2020 Nobel Prize in Chemistry

The Royal Swedish Academy of Sciences has awarded this year’s Nobel Prize in Chemistry to NeuroCure PI Prof. Dr. Emmanuelle Charpentier, Scientific and Managing Director of the newly established Max Planck Unit for the Science of Pathogens in Berlin for her groundbreaking work on the CRISPR-Cas9 gene editing technology. She shares the prize with Jennifer Doudna from the University of California, Berkeley, USA.

Read more … Emmanuelle Charpentier honoured with the 2020 Nobel Prize in Chemistry

Organoids and sequencing team up for ALS research

MDC researchers received a $150,000 pilot project grant from the Chan Zuckerberg Initiative’s Neurodegeneration Challenge Network to investigate a defining feature of amyotrophic lateral sclerosis (ALS).

Read more … Organoids and sequencing team up for ALS research

ECN and NeuroCure join the FENS 2020 Virtual Forum

One of the largest international meetings of neuroscientists, the Federation of European Neuroscience Societies (FENS), went virtual this year from 11-15 July 2020, offering five days of lectures, posters, symposia, exhibitions, networking and development opportunities.

Read more … ECN and NeuroCure join the FENS 2020 Virtual Forum

“Research in Germany” Virtual Fair 2020

ECN’s booth at the “Research in Germany” virtual career fair this year saw nearly 500 visitors. The chatroom was fully booked for every minute of the four-hour event as dozens of students expressed interest in the program and asked questions about the curriculum, lab rotations, and the application process and requirements.

Read more … “Research in Germany” Virtual Fair 2020

Workshop at the 29th Annual Computational Neuroscience Meeting 2020

During the Annual Computational Neuroscience Meeting 2020 – ECN fellow Alexandra Tzilivaki organizes a workshop entitled: Dissecting the role of interneurons in mnemonic functions using computational modelling approaches."

Read more … Workshop at the 29th Annual Computational Neuroscience Meeting 2020

Osmotic stress identified as stimulator of cellular waste disposal

Cellular waste disposal, where autophagy and lysosomes interact, performs elementary functions, such as degrading damaged protein molecules, which impair cellular function, and reintroducing the resulting building blocks such as amino acids into the metabolic system. This recycling process is known to keep cells young and, for instance, protects against protein aggregation, which occurs in neurodegenerative diseases. But what, apart from starvation, actually gets this important system going?

Read more … Osmotic stress identified as stimulator of cellular waste disposal

ECN at Research in Germany virtual fair

Meet us at the Research in Germany virtual fair on academic careers in #Germany and learn more about the

ECN and the ECN Fellowship program. Save the date: 07 July 2020!

Read more … ECN at Research in Germany virtual fair

Translating academic careers into industry healthcare professions

Though academic institutions have contributed enormously to the remarkable growth in the healthcare industry, a key limiting resource for this continued growth is the creation of career opportunities for doctoral graduates.

Read more … Translating academic careers into industry healthcare professions

Discovery of important molecular mechanism of Charcot-Marie-Tooth disease

Charcot-Marie-Tooth (CMT) disease is the most common form of inherited neuropathies. A genetic mutation causes the insulating myelin layer of peripheral nerves to become progressively damaged, resulting in severe disabilities in the case of CMT type 4B, for instance. Since the molecular basis is largely unknown, this type of CMT is untreatable and incurable to this day. Now researchers from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) in Berlin, in collaboration with colleagues from Milan, Paris and Mexico, have been able to highlight a new molecular mechanism.

Read more … Discovery of important molecular mechanism of Charcot-Marie-Tooth disease

The Long Night of the Sciences 2020

This year everything is different: Due to the Corona crisis, the Long Night of Sciences 2020 has also been cancelled. Nevertheless, the Long Night of Sciences 2020 has taken place on the radio.

Read more … The Long Night of the Sciences 2020

DFG approves new Transregional Collaborative Research Center for Neuromodulation

Many neurological disorders are associated with impaired movement. Neuromodulation, the targeted electrical stimulation of nerve cells, can help to control altered neuronal network activity. A new Transregional Collaborative Research Center (SFB/Transregio) will now study the nature of the neuromodulation mechanisms which are responsible for a range of conditions.

Read more … DFG approves new Transregional Collaborative Research Center for Neuromodulation

Peter Hegemann receives 2020 Shaw Prize

Gero Miesenböck, Peter Hegemann and Georg Nagel receive the 2020 Prize in Life Science & Medicine!

Read more … Peter Hegemann receives 2020 Shaw Prize

New ECN Website Section: Mental Health

Happy to announce our new website section Mental Health in cooperation with Scholar Minds, which is a self-organized-initiative of PhD students at Charité – Universitätsmedizin Berlin and Humboldt-Universität zu Berlin trying to provide the Berlin neuroscience community with some relief.

Read more … New ECN Website Section: Mental Health

Scientists decipher further mechanism for memory formation

A research group led by Professor Dietmar Schmitz of Charité - Universitätsmedizin Berlin has pinpointed the area of the brain involved in transferring memory-associated information into long-term memory. The results have now been published in Nature Communications*.

Read more … Scientists decipher further mechanism for memory formation

Understanding the Formation of Nerve Cell Contacts - Volker Haucke receives 2.5 Million Euros of Funding from the European Research Council (ERC)

Professor Volker Haucke from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) and the Freie Universität Berlin receives a prestigious ERC Advanced Grant of the European Research Council (ERC). The biochemist is granted a total funding of up to 2.5 million euros for a period of five years for his highly innovative research on the assembly of synapses.

Read more … Understanding the Formation of Nerve Cell Contacts - Volker Haucke receives 2.5 Million Euros of Funding from the European Research Council (ERC)

ERC Advanced Grant awarded to project MatCo

The ECN is delighted to congratulate Prof. Dr. Dr. Friedemann Pulvermüller for receving an European Research Council (ERC) Advanced Grant.

 

Read more … ERC Advanced Grant awarded to project MatCo

Limbic encephalitis: autoantibodies trigger overexcitation in the brain

A current research project underway at the German Center for Neurodegenerative Diseases (DZNE), in cooperation with the NeuroCure Cluster of Excellence at Charité-Universitätsmedizin Berlin, suggests that individual antibodies from the cerebrospinal fluid of patients with limbic encephalitis, a certain form of autoimmune encephalitis, increases the excitability of nerve cells. This finding moves us in the direction of a better understanding of the disease. The results have been published in the journal Annals of Neurology* (Ann Neurol 2020; 87: 405-418).

Read more … Limbic encephalitis: autoantibodies trigger overexcitation in the brain

General Anesthesia Decouples Cortical Pyramidal Neurons

The mystery of general anesthesia is that it specifically suppresses consciousness by disrupting feedback signaling in the brain, even when feedforward signaling and basic neuronal function are left relatively unchanged. The mechanism for such selectiveness is unknown. A team of scientists from Germany (Matthew Larkum & Suzuki Mototaka, Humboldt University of Berlin) showed that three different anesthetics have the same disruptive influence on signaling along apical dendrites in cortical layer 5 pyramidal neurons in mice. 

Read more … General Anesthesia Decouples Cortical Pyramidal Neurons

Scientists Uncover a Never-Before-Seen Type of Signal Occurring in The Human Brain

A team of scientists from Germany (Matthew Larkum, Humboldt University of Berlin) and Greece (Panayiota Poirazi, Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology - Hellas (IMBB-FORTH)) have discovered a unique form of cell messaging occurring in the human brain that's not been seen before.

Read more … Scientists Uncover a Never-Before-Seen Type of Signal Occurring in The Human Brain