Elisa Filevich

PhD

Affiliation

tba

Research area primary
systems/cognitive

Research area secondary
clinical/translational

Research Methods
experimental
human brain imaging
computational
cognitive neuroscience

Research Focus

Our group investigates the neural bases of metacognition of internally-generated processes, defined as those that cannot be directly related to a single event in the external world. We focus on the metacognition of motor control, motor imagery and motor intentions. We collect behavioural data in the lab and online and also do electroencephalography (EEG) and structural and functional magnetig resonance imagining (fMRI).

Craig Garner

Prof. Dr.

Affiliation

retired

Research area primary
cellular/molecular

Research area secondary
clinical/translational

Research Methods
experimental
cellular imaging
molecular

Research Focus

Our group is focused on understanding the molecular, cellular and physiological mechanisms regulating the dynamic assembly and function of vertebrate CNS synapses. Here we are seeking to define the cellular programs that control the dynamic exchange and degradation of pre- and postsynaptic proteins govern the formation, maintenance and integrity of synapses. We are also interested in understanding how genetic and environmental insults adversely influence these programs, leading to synapse dysfunction and/or neuronal degeneration.

Rosemarie Grantyn

Prof. Dr.

Prof. Dr. Rosemarie Grantyn

Affiliation

retired

Research area primary
cellular/molecular

Research area secondary
systems/cognitive

Research Methods
experimental
cellular
electrophysiology
optogenetics

Research Focus

Our research focuses on astrocyte-related mechanisms in the pathogenesis and treatment of Huntington’s disease. Astrocyte leaflets in proximity to axodendritic release sites are involved in the recycling of neurotransmitters and control the formation, maintenance and plasticity of synaptic domains. Insufficient clearance of glutamate at synaptic sites is considered as a cause of abnormal network activity in the HD striatum. We pursue the aim to ameliorate the motor symptoms of HD by adenoviral gene transfer recovering normal astrocyte-synapse interactions in the corticostriatal pathway.

Hauke Heekeren

Prof. Dr.

Affiliation

Präsident der Universität Hamburg, Mittelweg 177, 20148 Hamburg

Research area primary
systems/cognitive

Research Methods
experimental
computational

Research Focus

I am interested in the cognitive neuroscience of human decision making. My research group studies basic mechanisms of perceptual, value-based, and social decision making using behavioral methods, cognitive modeling as well as human brain imaging methods (such as fMRI and EEG)

Halina Machelska

Prof. Dr.

Affiliation

tba

Research area primary
cellular/molecular

Research area secondary
clinical/translational

Research Methods
experimental
cellular
biochemical
in vivo rodent models

Research Focus

- Pathophysiology of chronic pain (inflammatory, neuropathic, postoperative, arthritis)
- Cellular and translational approaches in pain modulation
- Neuroimmune interactions for pain control
- Neuropharmacology, nanopharmacology (opioids, ion channels)
- Nonpharmacological, noninvasive approaches for pain treatment

Philipp Sterzer

Prof. Dr.

Prof. Dr. Philipp Sterzer

Affiliation

Translational Psychiatry, Psychiatric Hospital of the University of Basel, Switzerland

Research area primary
systems/cognitive

Research area secondary
clinical/translational

Research Methods
experimental
human brain imaging
computational
cognitive neuroscience

Research Focus

We use fMRI, psychophysics, eye tracking and computational modelling to study human visual perception. The main research focus is on understanding the neural basis of conscious visual perception and alterations of perceptual processes in mental diseases, with a focus on schizophrenia. Current projects use the computational framework of predictive coding to investigate the role of learning and expectations in the context of perceptual ambiguity, learing and decision making. Another focus of our research is on the unconscious processing of visual information.

Baris Tursun

Dr.

Affiliation

Molecular Cell Biology Unit, Biology Department, Institute of Cell and Systems Biology of Animals, University of Hamburg

Research area primary
cellular/molecular

Research area secondary
clinical/translational

Research Methods
experimental
cellular
molecular

Research Focus

We use C. elegans as a genetic model organism to study the molecular basis of cell fate maintenance and protection in order to improve direct reprogramming of different cells into neurons. By imaging cellular reprogramming in vivo combined with visual genetic screens, we identified chromatin factors that safeguard cell fates and act as a barrier for direct reprogramming of non-neuronal cells to specific neurons. Together with our studies on the interconnection of Aging and cell fate protection our findings could help to overcome the limitations of Direct Reprogramming in other systems.